Use official specifications and past papers as the source of truth: AQA, Pearson Edexcel and OCR. StudyVector is independent and is not affiliated with any exam board.
Predicted paper
Edexcel GCSE Biology 2026 Predicted Practice Paper — Paper 1 Higher
GCSE Biology · Edexcel-style · 105 minutes · 100 marks
Modelled component: 1BI0/1H · Tier: Higher · Calculator permitted
Models Pearson Edexcel GCSE Biology Paper 1 Higher: 1 hour 45 minutes, 100 marks.
Prediction type: predicted_paper · Evidence mode: historical · Full-length original practice paper modelled on Pearson Edexcel GCSE Biology public paper structure. It is not official, leaked or guaranteed.
Evidence basis: official public assessment structure, full-paper mark total, board-specific paper code, GCSE Biology topic weighting, required-practical and data-response mix.
67
0–100 model (higher = more demanding)
- Cells and control
- Genetics
- Natural selection
- Monoclonal antibodies
- Drug testing
- Homeostasis
I completed a StudyVector GCSE Biology derived predicted-practice paper (2026) and scored 0/100. This is practice-only and not an official paper:
Section A
Answer all questions. This paper is written in a Pearson Edexcel Paper 1 practice style.
Question A1 (10 marks)
(a) Explain the difference between magnification and resolution. (3) (b) Describe how to prepare a microscope slide of plant cells. (4) (c) A cell is 40 mm in an image and 0.08 mm in real life. Calculate magnification. (3)
Question A2 (10 marks)
(a) Describe the stages of mitosis. (4) (b) Explain why mitosis is important for growth. (2) (c) Explain why stem cells are useful in medicine. (2) (d) Give one ethical concern about stem cell use. (2)
Question A3 (10 marks)
A person is heterozygous for a dominant allele B. (a) Define heterozygous. (2) (b) Draw or describe a genetic cross between Bb and Bb. (4) (c) State the expected phenotype ratio if B is dominant. (2) (d) Explain why actual offspring numbers may differ from the expected ratio. (2)
Question A4 (10 marks)
(a) Explain natural selection using antibiotic resistance as an example. (5) (b) Describe one difference between selective breeding and genetic modification. (3) (c) Give one risk of selective breeding. (2)
Question A5 (10 marks)
(a) Describe how monoclonal antibodies are produced in outline. (4) (b) Give one medical use of monoclonal antibodies. (2) (c) Explain one advantage and one limitation of using monoclonal antibodies. (4)
Section B
Answer all questions. Quantitative answers must show working.
Question B1 (10 marks)
A drug is tested before it is licensed. (a) Explain why preclinical testing is done. (3) (b) Describe the purpose of clinical trials. (4) (c) Explain why double-blind trials improve reliability. (3)
Question B2 (10 marks)
(a) Describe how the nervous system responds to touching a hot object. (5) (b) Explain the role of synapses. (3) (c) Give one reason reflex actions are useful. (2)
Question B3 (10 marks)
(a) Explain how insulin controls blood glucose concentration. (4) (b) Compare Type 1 and Type 2 diabetes. (4) (c) Give one treatment or management strategy for Type 2 diabetes. (2)
Question B4 (10 marks)
(a) Describe how enzymes are involved in digestion. (4) (b) Explain why bile helps lipid digestion. (3) (c) Describe how villi are adapted for absorption. (3)
Question B5 (10 marks)
(a) Describe how to investigate the effect of light intensity on photosynthesis. (5) (b) Explain why distance from the lamp affects light intensity. (2) (c) Give two control variables. (2) (d) Name one product of photosynthesis. (1)
Train weak areas
Turn this paper into targeted practice — adaptive questions on your exact board and topics.
Start smart practice